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Your position: 华谱科仪 »Home »Products »HPLC Columns »X Series » XCharge columns

XCharge columns

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  • Separation Performance Benchmark for Basic Compounds
  • Electrostatic Adjusting Technology
  • Perfect Balance and Independent Control in Hydrophobicity/Static

Asymmetric peak shapes of basic compounds are usually observed on conventional alkyl bonded column due to ionic interactions between the ionized basic solutes and oppositely charged silanol groups on the silica gel. And it will be worse when large sample amounts are injected. These problems can sometimes be overcome by reducing the activity of silanol groups, using high concentration of buffer solutions or raising pH value of the mobile phase. However, the limitations above for the separation of bases include serious destruction of stationary phase and poor solubility. Based on the unique electrostatic adjustment technology, XCharge columns have successfully realized the perfect balance in hydrophobicity/hydrophilicity and static on the surface of packings to improve performance. Most important, peak shapes and selectivity of basic compounds are, on XCharge columns have been greatly improved.

  • Sharp & Symmetric Peak Shape
  • High Loading Capacity column for Basic Compounds

Sharp & Symmetric Peak Shape
A huge challenge for the separation of alkaloids is to avoid the ionic interactions between silanol groups and ionized alkaloids.

Based on our unique "polar-copolymerized" preparation technology, XCharge not only shield the residual silanols but also achieve a balance control of electrostatic interaction on the column surface, which is capable to ensure to obtain perfect peak shape and high resolution for basic compounds.

High Loading Capacity column for Basic Compounds
The separation efficiency of basic compounds usually decreases sharply as the injection amount increases, which makes it difficult for their effective separation and purification.

XCharge columns have successfully addressed such problem and high resolution and symmetrical peak shapes for basic compounds can be obtained for the large injection amount. It will be helpful to the purification and impurity analysis for basic medicines.

产品名称 粒度 孔径 色谱柱规格 货号
XCharge C18 2.8μm 100Å 2.1 mm x 50 mm 18190310205
      2.1 mm x 100 mm 18190310210
      2.1 mm x 150 mm 18190310215
      3.0 mm x 50 mm 18190310305
      3.0 mm x 100 mm 18190310310
      3.0 mm x 150 mm 18190310315
      4.6 mm x 100 mm 18190310510
      4.6 mm x 150 mm 18190310515
         
  5μm 100Å 2.1 mm x 50 mm 18190510205
      2.1 mm x 100 mm 18190510210
      2.1 mm x 150 mm 18190510215
      3.0 mm x 50 mm 18190510305
      3.0 mm x 100 mm 18190510310
      3.0 mm x 150 mm 18190510315
      4.6 mm x 150 mm 18190510515
      4.6 mm x 250 mm 18190510525
      7.8 mm x 150 mm 18190510815
      7.8 mm x 250 mm 18190510825
      10.0 mm x 150 mm 18190511015
      10.0 mm x 250 mm 18190511025
         
  10μm 100Å 4.6 mm x 150 mm 18191010515
      4.6 mm x 250 mm 18191010525
      7.8 mm x 150 mm 18191010815
      7.8 mm x 250 mm 18191010825
      10.0 mm x 150 mm 18191011015
      10.0 mm x 250 mm 18191011025
      20.0 mm x 150 mm 18191012015
      20.0 mm x 250 mm 18191012025